Search Results for: DNA
The flipside of DNA: Flipons and alternative nucleic acid structures
DNA sequences called flipons can adopt alternative DNA structures. New research suggests that they have important biological roles. In a quest to further unravel the mystery of these dynamic DNA […]
Artemis:DNA-PKcs: A new drug target for cancer treatment?
Cells encounter DNA double-strand breaks (DSBs) every day. Because they can lead to loss of genetic information, DSBs must be repaired. Nonhomologous DNA end joining (NHEJ) is the major pathway […]
DNA molecular scissors as new cancer chemotherapeutics
The discovery of efficient new metallodrugs with minimal side effects is urgently needed in cancer medicine. Associate Professor Andrew Kellett and Dr Creina Slator, Dublin City University, Ireland, have employed […]
The role of extra chromosomal circular DNA in rapid adaption to glyphosate resistance in pigweed
Plants, like other living organisms, have genetic stress-avoidance mechanisms that allow them to become resistant to specific chemicals when continuously exposed to them. Dr Christopher Saski from Clemson University and […]
Identifying the mitochondrial DNA mutations that cause cancer
Mutations that affect the mitochondrial DNA may play a key role in cancers. However, the exact mutations that are involved in cancer are still unknown. Dr Fatimata Mbaye and collaborators, […]
Producing the first functioning synthetic DNA using click chemistry
Click chemistry revolutionised our ability to create custom proteins, so could it do the same for DNA? Professor Tom Brown at the University of Oxford and Professor Afaf El-Sagheer at […]
Dancing DNA: How Rad51 chooses the perfect partner
Professor Hiroshi Iwasaki, Tokyo Institute of Technology, aims to learn more about a biological process called homologous recombination, which is crucial to maintaining the integrity of DNA. His laboratory-based research […]
Directed Panspermia: Synthetic DNA in bioforming planets
As our technological advancements continue, scientists are beginning to turn what was science fiction into reality. Concepts such as terraforming and travel between stars are becoming more achievable, giving life […]
DNA untangled: Topoisomerase enzymes remove our genetic knots
Topoisomerases are enzymes that are abundantly present in our cells and can temporarily cut and rejoin our DNA to remove knots and tangles that form during important biological processes. If […]
Z-DNA the new biology: The third dimension of cancer therapeutics
DNA comes in many different shapes and sizes. Z-DNA, also known as left-handed DNA, is different from the more familiar right-handed B-DNA. Until recently, the role of Z-DNA in humans […]