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Glycomimetic peptides as powerful anti-inflammatory treatments

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Glycan (sugar)-binding lectin-type receptors on immune cells have the potential to serve as therapeutic targets. However, many of these receptors are not targeted because of a lack of suitable binding […]

Impact of dietary protein on cat health and wellbeing

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Compared to dogs, cats require higher levels of protein in their diet to remain healthy. Based on current recommendations, commercially available cat food contains between 28% and 55% protein for […]

Heart health, fat consumption and low-density lipoprotein cholesterol

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Cardiovascular disease is a major contributor to deaths globally. One of the most prominent risk factors for cardiovascular diseases (CVD) is low-density lipoprotein cholesterol (LDL). Special focus has been placed […]

Novel insights into parasite dynamics for leishmaniasis treatment

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Neglected tropical diseases such as leishmaniasis have a huge impact on global health but are under-researched and under-funded. Treatment and diagnostic techniques remain expensive and difficult to implement in remote […]

Increasing the efficacy of monoclonal antibodies

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The advent of monoclonal antibody (mAb) technology has allowed the production of antibodies that can target specific antigens on malignant tumour cells or other inflammatory molecules that are known to […]

How did bacterial glycogen branching enzymes evolve?

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Glycogen is a sugar which plays important roles in carbon and energy storage in bacteria. Glycogen with a highly branched, compact structure offers a more durable energy source – a […]

Using β3 integrin to control reactive astrocytes, and help neurons survive

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The long-ignored astrocyte is of more interest than ever in neuroscience. When the central nervous system is damaged, astrocytes undergo astrogliosis, morphing into reactive astrocytes to protect neurons from further […]

Engineering virus nanoparticles to modulate coagulation

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Using chemistry, Dr Andrew K. Udit, Occidental College, Los Angeles, is exploring novel ways that bacteria-infecting viruses (bacteriophage) may be able to reverse the anti-clotting effects of heparin. By specifically […]

Seeing the structures of molecules: insights from NMR and industry

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Many of the essential chemical constituents of life, including carbohydrates, are made up of complex atomic arrangements. Knowing the particular structure of a compound is important not only for identification […]

New hope for muscular dystrophy treatment

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Muscular dystrophy (MD) is a family of genetic diseases which cause muscular weakness. Their severity varies but all are progressive and many are ultimately terminal. Until now, therapy options have […]