Health & Medicine

Developing a novel inhaled therapeutic for the treatment of bronchiolitis obliterans syndrome

Breath Therapeutics – a Zambon Group Company, is a clinical stage biopharmaceutical company specialising in advanced inhaled therapeutics for severe respiratory diseases. The company’s proprietary liposomal drug formulation has been specifically designed for inhaled administration with an exclusively licensed nebulizer technology. Liposomal cyclosporine A for inhalation (L-CsA-i), an investigational drug, is advancing in phase 3 clinical trials as the first […]

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Biology

Understanding the olfactory system

The recent discovery of endogenous cannabinoids has kickstarted a whole area of research into their function. Cannabinoids have been widely studied in the hippocampus and amygdala of the brain but their role in other regions, including the olfactory system, are largely a mystery. Professor Thomas Heinbockel and his team from Howard University College of Medicine research cannabinoids in the olfactory […]

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Arts & Humanities

Splendid or melancholy isolation

With masterpieces guaranteed to pull in the crowds, museum curators pay close attention to how these works are displayed, whether grouped together or in isolation in a specially conceived room. In her research for the École du Louvre and the University of Neuchâtel, Professor Cecilia Hurley explores the notion of the masterpiece, the utility of museums and how this effects […]

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Physical Sciences

Shining a light on photochemical dynamics

When a molecule absorbs light, this can trigger a whole host of reactions. This includes the formation of new bonds or even rearranging the order of the atoms within the same molecule to create new chemical species. These light-induced changes, known as photochemical dynamics, can be challenging to study as they can occur on timescales of femtoseconds, so fast that […]

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Physical Sciences

Search for dark matter with cool crystals

Dark matter is one of the most elusive constituents in the universe; escaping our detection for decades since astronomers first theorised its existence. In his research, Dr Jing Liu at the University of South Dakota proposes an unconventional usage of light-emitting crystals to detect dark matter produced in particle accelerators on the Earth. His team is prototyping a detector consisting […]

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Biology

Biomimetic assembly of multienzyme reactions on DNA nanostructures

Using DNA nanotechonology, researchers from Rutgers University-Camden have created self-assembly biomimetic systems capable of enzyme proximity immobilisation and enzyme compartmentalisation. Remarkably, these structures have proven themselves capable of forming a multi-enzyme cascade with substrate channeling and regulated reaction circuit. The potential for future applications of this research are wide-ranging and include healthcare and biomedical research to energy release and chemical […]

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Health & Medicine

PACT: Working with parents and carers to help autism development

Autism is an enduring condition affecting over 1% of people worldwide but with a lack of evidenced therapy to reduce its symptoms. PACT is an early social communication intervention working through parents and carers that is the first to have demonstrated long-term improvements in autism symptoms after therapy within a clinical trial. This relatively low intensity approach is referenced in […]

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Informatics & Technology

Reproducible computer vision.
Cross-disciplinary and scalable image informatics

The LIMPID, or Large-Scale IMage Processing Infrastructure Development project aims to help scientists around the world to share information and advance the reproducibility of methods in the field of computer vision – or how computers ‘see’ and analyse images. The LIMPID project has applications in fields as diverse as materials science, biology, neuroscience, marine science, remote sensing, and medicine. The […]

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Physical Sciences

Understanding the effects of humidity on ionic liquid-based electrochemical gas sensors

Electrochemical gas sensors are critically important tools used in a wide variety of everyday tasks, but with current designs, their performance can be significantly diminished in hot, dry conditions. Debbie Silvester at Curtin University, Australia suggests that this problem could be overcome through the use of specialised salts, which remain liquid at room temperature. While these substances are known to […]

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