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Targeting the curvature of cell membranes for parasitic infection treatment

  Cell membranes are crowded and dynamic places. They constitute the first contact for all external stimuli that arrive at a cell, and are in charge of transmitting this information to the cell interior. This works through a cascade of metabolic steps, performed by several phospholipases, amongst other enzymes. Phospholipases degrade membrane components and form signal messengers, which transmit chemical […]

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Magnitude of uncontrolled hypertension, and associated factors, amongst adult hypertensive patients in public hospitals of Central Zone, Tigray, Ethiopia, 2018

  Uncontrolled hypertension For the general hypertensive population, uncontrolled hypertension (high blood pressure) is if the systolic blood pressure (SBP) is ≥140 mm Hg and/or diastolic blood pressure (DBP) is ≥90mm Hg. For inpatients with established diabetes mellitus or chronic kidney disease – it’s when SBP is ≥130 mm Hg and/or DBP is ≥80mm Hg. Blood pressure results are based on […]

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Another archive is possible

And   There is a slogan, popularised by the anti-globalisation movement,  already commonly deployed in the lexicon of social movements militancy, which states: ‘another world is possible.’ But is another archive possible? There are archives that are created from material that, in principle, are not the object of archival science, but become so due to special circumstances – such as […]

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Recognition of urban water bodies using deep learning with multi-source and multi-temporal high spatial resolution remote sensing imagery

  Data from High Spatial Resolution Remote Sensing Imagery (HSRRSI) provides detailed information required for the recognition of surface water bodies, including the texture, geometric structure and spatial distribution of these liquid masses. The comprehensive information gathered means that the internal components of surface water bodies can be represented, and the relationship between adjacent objects are better reflected. In the […]

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How does genetics affect the way we taste salt and how our blood pressure responds to it? Implications for personalised dietary recommendations

  Salt sensitivity of blood pressure is defined as an increase in blood pressure after consuming large amounts of salt. While in salt-sensitive people we observe a salt-induced increase in blood pressure, in salt-resistant individuals such an increase is not observed. Salt-sensitive individuals may be at an increased risk of high blood pressure and cardiovascular disease later in life. Salt […]

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Femtosecond laser surface structures obtained with nanosecond laser pulses

  Usually, a material itself defines the properties of its surface. For example, the wettability of surfaces depends on the chemical composition, the possibility for hydrogen bonding towards the surface and several other aspects. To change the surface property of a material, coatings with specialized paints are a routine technique, for example to increase the emissivity of radiators with radiator […]

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Quantum simulation for solving the waste plastics problem

  Plastics are ubiquitous, convenient, and cheap. So, it is not a surprise that the world manufactures 359 million metric tons (Garside, 2020) of plastics every year. Most plastics are yet not readily biodegradable. As a result, at the end of life, 55% (Ritchie and Roser, 2018) of all waste plastics find their way into landfills, or are illegally dumped […]

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Increase viability and efficiency in the design and development of new plant varieties through molecular assisted breeding in the postgenomic era

Design of new plant varieties: an increasingly complicated task We can consider plant breeding as an applied science of design which requires empirical support based on observation and experimentation. At the same time, plant breeding is a design science, as it comes up with models to meet aims that expand human possibilities. In fact, the design of new varieties involves […]

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Atypical presentation of spontaneous spinal epidural hematoma

Introduction Spinal epidural is an uncommon diagnosis, making out less than 1% of all the compressive lesions in the vertebral column (1, 2). Spontaneous spinal epidural hematoma (SSED) designates a condition in which there is blood within the epidural space without any known trauma or iatrogenic triggering event. The incidence has been reported to 0, 1 in 100000 person years […]

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