Conquering sunlight sensitivity: Dersimelagon’s promise in photodermatoses

Dersimelagon in Erythropoietic Protoporphyrias

Two rare genetic dermatological conditions, erythropoietic protoporphyria and X-linked protoporphyria, bring about excruciating pain and skin damage upon exposure to sunlight. In groundbreaking research, a new medication called dersimelagon is addressing these conditions. Led by Dr Kirstine Belongie and her expert team at Mitsubishi Tanabe Pharma America, a clinical trial was conducted to evaluate dersimelagon’s impact on the onset time […]

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A role for ultraviolet radiation in multiple sclerosis

Dr George E Davis investigates the relationship between UV radiation, geographic latitude, and the role of vitamin D in the autoimmune disease multiple sclerosis.

There are more cases of multiple sclerosis (MS), a condition caused by impaired immune responses, in northern countries compared to southern countries. Dr George E Davis, who is affiliated with the Riverview Psychiatric Centre, Maine, USA, has explored the links between latitude, MS, and UV radiation. He puts forward the idea that UV radiation levels during month of conception offer […]

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Melanin – a protector from skin cancer

Skin cancer is one of the most common malignant tumours worldwide.

Skin cancer is a worldwide problem and is more common in people with lighter skin than people with darker skin colour. Ultraviolet (UV) radiation is the primary contributor to skin cancer development by causing DNA damage in skin cells called keratinocytes. Melanin, the pigment responsible for skin colour, also plays a role in generating so-called melanin caps – umbrella-like structures […]

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Atmospheric species and their effect on solar radiation and our health

Bai and Chen created a model that describes seasonal and daily patterns and trends in the amount of radiation exposure.

Our atmosphere is a giant chemical reactor that helps keep us safe from the potentially damaging and warming effects of solar radiation. It consists of a hugely complex mixture of atmospheric liquids, gases, and particles with constantly varying compositions. Professor Jianhui Bai at the Chinese Academy of Sciences and Professor Rui Chen at the Beijing Academy of Science and Technology […]

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