Health & Medicine

Virtual navigation exposes the reality of Alzheimer’s disease onset

Prof Zahra Moussavi from the Faculty of Engineering at the University of Manitoba in Canada has developed a novel method of assessing patients for Alzheimer’s disease. Using a virtual reality environment to measure spatial awareness, she has shown key differences between control and patient groups, leading to pilot studies for effective early treatment. Prof Zahra Moussavi became interested in early […]

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Health & Medicine

Swimming against the stream: modern-day challenges to male reproductive health

The effects of a mother’s age, health and habits upon her offspring are well documented. However, far less attention has been paid to fathers. Dr Bernard Robaire, Professor at McGill University, Montréal, Canada, believes male reproductive health may be just as important for future generations as that of females, with a father’s age, health and exposure to chemicals all having […]

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Health & Medicine

Fluoxetine (Prozac) use in children: working towards a customised approach

Dr Mari Golub from the Environmental Toxicology Department at the University of California at Davis, has recently completed a five-year research project looking at the behavioural effects of fluoxetine (Prozac) on brain development. Her findings, which have so far been published in eight academic papers, supplement information on the safety of fluoxetine use in children, and show for the first […]

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Health & Medicine

Controlling magnesium flux: a central role for the PRL-CNNM complex

Magnesium is an essential metal ion for human health. However, its ability to act as a supplementary therapy against disease is a poorly understood area of science. Professor Michel L. Tremblay and his team at McGill University in Montreal, Canada, are looking to change this though, and are currently investigating the role of the newly discovered pathway, PRL-CNNM, in controlling […]

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Health & Medicine

Blood, skin and bone: the complex control of blood pressure

It is well-known that excessive salt intake can be a risk factor for high blood pressure. But how this effect is mediated – and why some people are more susceptible than others – remains up for debate. Collaborators Professor Raymond Harris and Professor Ming-Zhi Zhang, at Vanderbilt University School of Medicine, have uncovered a novel role for immune cells derived […]

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Health & Medicine

Disordered fat storage enhances development of type 2 diabetes

Diabetes is a devastating, life-changing condition. Professor André Carpentier and his colleagues from Université de Sherbrooke are exploring how obesity increases the risk of type 2 diabetes. After all, abnormal fat storage can lead to insulin resistance, which endangers organ function. Through his and his team’s research, Dr Carpentier aims to develop therapeutic measures which reverse detrimental pre-diabetic effects. In […]

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Health & Medicine

The genomics of cancer

Many cancers are associated with changes to our genetic material, DNA. These may be small, single unit substitutions, large rearrangements such as deletions or duplications of a part of the DNA sequence, or various other forms of mutations. Although the smaller substitutions have been more intensively studied, Dr Lixing Yang, of the University of Chicago, focuses on uncovering changes at […]

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Health & Medicine

Reprogramming the immune system for personalised immunotherapy against cancer

For decades, researchers have strived to understand how the immune system recognises and fights cancer, ultimately aiming to exploit and augment these processes to create more effective cancer therapies. Dr Richard Koya, Associate Professor of Oncology, Associate Director of the Center for Immunotherapy, and Director of the Vector Development & Production Facility at Roswell Park Cancer Institute is a prominent […]

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Health & Medicine

Inhibiting cancer stem cell survival in the hostile tumour environment

Wouldn’t it be great if a small non-toxic molecule could be used to treat cancer? By investigating the possibility of using a cancer cell’s own physiology as a weapon against it, Dr Shoukat Dedhar, at the University of British Columbia, is developing a new treatment that could help prevent tumour growth and metastasis. Every two minutes, someone in the UK […]

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Health & Medicine

A new class of antibiotic drugs

Finding new classes of antibiotic drugs could not only save human lives, but also greatly reduce the healthcare costs related to tackling bacteria resistant to currently available drugs. Professor Chris McMaster, director of the Cheminformatics Drug Discovery Lab at Dalhousie University in Halifax, Canada, is developing a new class of antibiotics, while trying to overcome the many challenges associated with […]

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