Myocardial lipid metabolism: Targeting CD36 to treat cardiac disease

Jan Glatz researches a transmembrane protein, CD36, which regulates cellular lipid metabolism and can lead to treatments to improve healthy heart contraction and treat cardiac disease.

Jan Glatz, Emeritus Professor of Cardiac Metabolism at Maastricht University, conducts research into the transmembrane protein CD36, which regulates cellular lipid metabolism. CD36 facilitates the uptake of long-chain fatty acids in cardiac muscles while the recycling of CD36 between endosomes and the sarcolemma regulates this uptake. Heart diseases are commonly associated with changes in the uptake and use of its […]

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