Case Western Reserve University Archives

A pilot volunteer reader program decreases delirium days in critically ill ICU patients

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Delirium is a form of acute brain failure that alters mental status and affects proper memory, emotion, and behavior, developing over hours to days. Between 20-80% of ICU patients develop delirium, depending upon the tools used for diagnosis. Delirium is commonly overlooked because only 25% of delirium patients present with hyperactivity, that is, showing evidence of hallucinations and agitation. More […]

Plant phytochemicals. A new cancer chemopreventative?

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Dr Sanjay Gupta from Case Western Reserve University is exploring the chemopreventative properties of phytochemicals such as polyphenols and flavonoids, found in plants. The team aim to enhance our understanding of the epigenetic mechanisms that are influenced by phytochemicals resulting in cancer prevention. By manipulating gene expression, without changing the genetic code, phytochemicals can inhibit both oxidative stress and […]