Tag: CDAP

Conjugation chemistry creates affordable childhood vaccines

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Andrew Lees has developed a conjugation method for the development of conjugate vaccines using the chemical CDAP, and combining this with a minimal-profit business model, is providing vaccines at affordable rates to children in developing countries.

The immune system provides a formidable defence against pathogens. However, many bacteria possess a protective sugar polymer coat. In children, the immune system does not respond to these polymers unless they are chemically linked to a carrier. This is the basis of conjugate vaccines, a powerful but expensive means to fight diseases like pneumonia, the leading cause of death in […]

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