Synthesising circular RNA is as easy as PIE

Dr Jason Rausch has developed a new protocol for synthesising large, complex, artificial circRNA which enhances the research in this field, as these have significant functionality and can also be genetic biomarkers for certain diseases

Naturally occurring circular loops of RNA, circRNAs, are the result of rare but significant backsplicing events. They are found throughout the eukaryotic domain and have been associated with pathological states such as tumour growth and suppression. Existing molecular techniques have taught us a great deal about circRNAs, but they are often difficult to implement and limited in scope. Dr Jason […]

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