Synthesising circular RNA is as easy as PIE

Dr Jason Rausch has developed a new protocol for synthesising large, complex, artificial circRNA which enhances the research in this field, as these have significant functionality and can also be genetic biomarkers for certain diseases

Naturally occurring circular loops of RNA, circRNAs, are the result of rare but significant backsplicing events. They are found throughout the eukaryotic domain and have been associated with pathological states such as tumour growth and suppression. Existing molecular techniques have taught us a great deal about circRNAs, but they are often difficult to implement and limited in scope. Dr Jason […]

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Getting retting better by bacterial blending

jute undergoes the retting process

Jute is the second most important fibre crop after cotton. Harvesting of jute is followed by retting, where the fibres are separated from stems. This is performed in open waters where natural microorganisms decompose the plant material. The fibre quality depends on retting efficiency. Given the water scarcity in Bangladesh and the resulting delays in harvest, the quality of fibres […]

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Pure and sound: Isolating the finest RNA from jute

products made from jute fibre

Jute is an important crop grown for human usage of its fibres in everyday materials. There has been an increasing interest to study the behaviour of this crop in the field, to maximise its yield. Detailed studies of this plant at the molecular level involves several techniques that require isolation of cellular material such as nucleic acids (DNA and RNA) […]

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From beer to brains: how yeast molecular genetics prove the importance of introns

A research article highlighting the importance of intron retention, using the GCR1 gene found in yeast as a model system.

Scientific discoveries often come from the most unlikely of places, and Dr Tracy Johnson’s work is no exception. Using a yeast system typically used to make beer or bread, Dr Johnson and her team at UCLA have uncovered important genetic findings that could highlight the importance of intron retention during gene expression. Her research looks at the science of gene […]

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