Stress vulnerability and resilience: Insights from a novel mouse model

A novel mouse model for early life adversity and stress, and the impact this can have in later life stress response and possible psychiatric disorders, has been developed.

Stress and early life adversity alter the body’s stress response and are predisposing individuals to psychiatric disorders. Additionally, stress vulnerability and resilience have a genetic predisposition in humans due to variants of the FKBP5 gene. For in depth understanding of underlying mechanisms altering the stress-response network, valid animal models are needed. A novel mouse line developed at Taconic Biosciences and […]

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