Articles
Identification of a novel key player in lupus disease opens the door to treatment
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, the precise cause of which is still unclear. Through dedicated work, Professor Shunichi Shiozawa from Kobe University, Japan, uncovers the underlying cellular and molecular mechanisms of systemic autoimmunity and identifies a novel key player. Shiozawa demonstrates that overstimulation of the host’s immune system by an immunogenic pathogen kickstarts the generation of […]
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Ending the debate: Routine or selective cholangiography during gallstone surgery?
Symptomatic gallstones are common in the Western world and treatment of choice is surgical removal of the gallbladder (cholecystectomy). During surgery, an x-ray procedure called intraoperative cholangiography (IOC) gives the surgeon information on the anatomy and whether gallstones have migrated from the gallbladder to the deep bile ducts. The procedure helps avoid certain surgical complications and prevent problems from retained […]
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Screening frailty: A predictor of healthcare requirements in older people
People are living longer, and this is associated with increased pressure on healthcare services. Assessing how much support people need allows resources to be used effectively and patients to receive the best care. Frailty is associated with poorer health and more complications – but the condition can be hard to characterise. Maider Mateo-Abad and Dr Itziar Vergara at the Biodonostia […]
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From friend to foe: Food strains share their toxic genes in E. coli
Food-borne bacteria can cause life-threatening disease, yet it is still unclear why some strains are tolerated by the host. To find an answer, a project led by Professor Rosa del Carmen Rocha-Gracia (Benemérita Universidad Autónoma de Puebla, Mexico) and Professor Manel Camps (University of California Santa Cruz, USA) analysed the genetic diversity of Escherichia coli populations, comparing isolates from food […]
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Metabolic dysfunction: The liver and beyond
The liver is the centre of our metabolism, with metabolic dysfunction playing a pivotal role in liver diseases and type 2 diabetes. Despite extensive study, the mechanisms underlying these pathologies remain largely unexplained. Professor Philipp Kaldis of Lund University, Sweden, has collaborated with fellow researchers to investigate the role of metabolites during metabolic dysfunction in these diseases. Motivated by the goal […]
Lead ammunition used by hunters has us all in its sights
For millions of people, game meat is their primary source of protein, but if the animal is shot using lead (Pb) ammunition, its meat can be toxic. The lead in the ammunition also finds its way into wildlife, ecosystems, and the global food chain, taking the poison far beyond the gun barrel. There are non-lead alternatives, but hunters are slow […]
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Urban Drone Operation: How wind in cities could affect air taxis of the future
In cities, many companies are now considering urban air mobility vehicles, from drones for parcel delivery to air taxis for travel. However, gusts of air, especially around buildings, can create pockets of wind with different properties, which could cause areas of turbulence and affect the stability of the aircraft. A research team led by Dr Abdulghani Mohamed, senior lecturer at […]
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Cut of the crop: High-yields of non-browning eggplant via genome editing
Eggplant is cultivated globally – but its production is fraught with issues affecting the crop’s overall yield and post-harvest properties. The fruit can be less appealing when damaged or cut due to the enzymatic browning of tissues. Cultivating high-yielding yet non-browning eggplants is an area of ongoing research at the Khalifa Center for Genetic Engineering and Biotechnology, UAE. The researchers […]
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Mechanochemistry: A new route to sustainable polymer recycling
Plastics and rubbers are some of the most important materials in advanced societies, and hundreds of millions of tonnes are produced every year. Devising efficient and cost-effective ways to recycle these materials has become a crucial environmental concern. Although degradable plastic-based materials can be produced, their practical use is limited by their vulnerability under environmental stress. Professor Junpeng Wang and […]
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Change by exchange: The German Academic Exchange Service (DAAD)
The German Academic Exchange Service (DAAD) is a large German education agency with global perspectives aimed at spreading the value of ‘exchange’ across borders and cultures through diverse, funded research projects. Research Outreach was privileged to talk with Kai Sicks, Secretary General of the DAAD, on the objectives, achievements, and future goals of the organisation. Many borders exist that prevent […]
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