animal models Archives

Usher syndrome: Recent advances in our understanding of genes and therapeutics

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Dr Aziz El-Amraoui and Dr Gwenaelle Geleoc research Usher syndrome, a genetic mutation in the USH1, USH2 and USH3 genes that causes hearing loss and vision loss.

Usher syndrome is a rare disease that affects the sensory systems of vision, hearing, and balance. Recent advances in scientific technologies reveal the genes involved in Usher syndrome, their varying phenotypic outcomes, and avenues for therapeutic development. Dr Aziz El-Amraoui of the Pasteur Institute in Paris, France, and Dr Gwenaelle Géléoc of Boston Children’s Hospital and Harvard Medical School in […]

Can animal-free research be the future of medical science?

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scientists undertake tests in a laboratory

Professor Merel Ritskes-Hoitinga from Radboud University, the Netherlands, aims to improve biomedical and medical research, reduce the use of unnecessary animal studies and replace animal studies by using better alternatives. Throughout her career she has researched and highlighted the disadvantages of animal studies, such as the substandard quality of results produced and lack of evidence for translatability to human clinical […]