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Rethinking the Tree of Life with new tools

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Dr Sung-Hou Kim has applied a new way of thinking to an old model, the Tree of Life, which dates back to Darwin.

Professor Sung-Hou Kim and his colleagues from the University of California, Berkeley, have applied a new way of thinking to the Tree of Life, a concept that has been around since Darwin’s time. Drawing from their collective expertise, they applied an Information Theory-based non-alignment method to compare whole-proteome sequences, the protein sequences coded by all genes of each organism. Their […]

Connectase: An enzyme that fuses proteins in a specific manner

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Dr Adrian Fuchs, post-doctoral researcher at the Max Planck Institute for Developmental Biology, and his team of researchers have discovered an enzyme that can fuse two proteins at specific recognition sites. This reaction enables the engineering of proteins with new characteristics, for example by labeling them with a detectable marker or by manipulating their interaction behaviour. Such applications are useful […]