Tag: dendrimers

Dendrimers: Improving calibration standards for mass spectrometry

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Professor Scott M Grayson has developed and optimised SpheriCal®, MS calibrants based on dendrimers – perfectly branched compounds, that offer better standards for calibration in mass spectrometry.

Soft-ionization mass spectrometry (MS) techniques for the analysis of peptides, proteins, and macromolecules are gaining popularity in the medical research community. Specifically, matrix-assisted laser-desorption/ionization (MALDI) and electrospray ionization (ESI) can identify high molecular weight compounds with accuracy and minimal fragmentation of the sample, but precise and regular calibration with standards of a known mass is needed. Professor Scott M Grayson […]

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