Amino acids bombarded with ionising radiation – what breaks first?

Radiation can cause abnormal cellular behaviour.

Ionising radiation, including high-energy electrons, is usually something best avoided. However, nuclear accidents and even medical tools mean that human tissue is occasionally exposed to it. After the ‘Atomic Age’ of the mid-1900s, understanding the effect of radiation on the human body has been recognised as of paramount importance. Dr Jelena Tamuliene’s most recent research at Vilnius University is into […]

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Proteomics reveals new possibilities in the fight against infection

Proteomics reveals new possibilities in the fight against infection

The work of Dr Jennifer Geddes-McAlister at the University of Guelph investigates the interactions between hosts and pathogens to uncover new treatment options to combat infections. Her lab uses a range of techniques centered around proteomics, the study of proteins, to progress knowledge of fungal and bacterial infections in humans and agricultural crops. The results of this research can be […]

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Therapeutic drug monitoring of methotrexate in disease

Therapeutic drug monitoring of methotrexate in disease

Professor Dr Robert de Jonge, Dr Gerrit Jansen, Ittai Muller MSc and Helen Gosselt MSc, Amsterdam University Medical Center, are pioneering analytical approaches which can be used to understand why patients respond differently to the anchor drug used to manage rheumatoid arthritis, called methotrexate. Their work has begun to unravel the key factors behind the mechanism of action of methotrexate, […]

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Let’s hear it for the proteome

Hearing loss is one of the most common sensory impairments, affecting 250 million people worldwide. The causes of deafness, such as exposure to loud noise, are relatively well known, but exactly how they result in hearing loss remains unclear. Dr Jeffrey Savas, Assistant Professor of Neurology at Northwestern University, Feinberg School of Medicine, USA, heads up a lab dedicated to […]

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