gene therapy Archives

Usher syndrome: Recent advances in our understanding of genes and therapeutics

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Dr Aziz El-Amraoui and Dr Gwenaelle Geleoc research Usher syndrome, a genetic mutation in the USH1, USH2 and USH3 genes that causes hearing loss and vision loss.

Usher syndrome is a rare disease that affects the sensory systems of vision, hearing, and balance. Recent advances in scientific technologies reveal the genes involved in Usher syndrome, their varying phenotypic outcomes, and avenues for therapeutic development. Dr Aziz El-Amraoui of the Pasteur Institute in Paris, France, and Dr Gwenaelle Géléoc of Boston Children’s Hospital and Harvard Medical School in […]

Promising potential treatment for ovarian cancer reaches final stages of clinical trials

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Dr Richard Penson and VBL Therapeutics are developing a new anti-ovarian cancer gene therapy treatment, VB-111

Ovarian cancer is one of the most dangerous forms of cancer. A treatment approach using platinum-based chemotherapy compounds is commonly used, however some tumour cells are resistant to the drugs used in this process. VBL Therapeutics is developing a promising new anti-cancer gene therapy: VB-111. With its unique dual mode of action, it targets the tumour environment by disrupting the […]