Tag: leishmaniasis
Novel insights into parasite dynamics for leishmaniasis treatment
Neglected tropical diseases such as leishmaniasis have a huge impact on global health but are under-researched and under-funded. Treatment and diagnostic techniques remain expensive and difficult to implement in remote areas. Dr Maria Fernanda Laranjeira-Silva of the University of Sao Paulo, Brazil, has been conducting research into potential new therapeutic targets, focusing on exploiting the parasite’s need to appropriate the […]
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Targeting the curvature of cell membranes for parasitic infection treatment
Cell membranes are crowded and dynamic places. They constitute the first contact for all external stimuli that arrive at a cell, and are in charge of transmitting this information to the cell interior. This works through a cascade of metabolic steps, performed by several phospholipases, amongst other enzymes. Phospholipases degrade membrane components and form signal messengers, which transmit chemical […]
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