Targeting the curvature of cell membranes for parasitic infection treatment

  Cell membranes are crowded and dynamic places. They constitute the first contact for all external stimuli that arrive at a cell, and are in charge of transmitting this information to the cell interior. This works through a cascade of metabolic steps, performed by several phospholipases, amongst other enzymes. Phospholipases degrade membrane components and form signal messengers, which transmit chemical […]

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Bacterial biofilms: A persisting public health challenge

Bacterial biofilms are a notable public health challenge.

Foodborne and waterborne diseases are major global health threats, exacerbated by the ability of bacteria to gain new characteristics, constantly evolve towards increased fitness in their environment, and by developing resilience through biofilm formation. Utilising emerging technologies such as elevated hydrostatic pressure and application of novel bacteriocin and bactericidal compounds, Professor Aliyar Cyrus Fouladkhah and his team in the Public […]

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Infectious bronchitis virus affects energy production

Infectious bronchitis virus affects energy production

Professor Tereza Cristina Cardoso, São Paulo State University, is a qualified veterinarian and her research explores infectious diseases in animals. Her latest work investigates how infectious bronchitis virus affects energy production by macrophage cells. Her research demonstrates that this occurs through disruption of mitochondrial respiration processes, which may have implications for how virus infections in poultry are prevented and treated. […]

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Changing climate: A ‘threat multiplier’ for foodborne and waterborne infectious diseases and antibiotic resistance

Aliyar Fouladkhah examines the risks of foodborne pathogens like Listeria monocytogenes.

Dr Aliyar Cyrus Fouladkhah of Tennessee State University is an Assistant Professor in Public Health Microbiology. His laboratory explores preventive measures for the spread of infectious diseases, antibiotic resistance, and food security in the landscape of changing climate. His research aims to provide better understanding of the ecology, epidemiology and effectiveness of control measures of enteric and environmental pathogens at […]

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Alpha-Gal syndrome Trade-off between allergy and protection to infectious diseases

Alpha-Gal syndrome Trade-off between allergy and protection to infectious diseases

Tick bites are responsible for the development of Alpha-Gal Syndrome (AGS) in humans. Resulting in severe allergies to red meat, tick bites and certain drugs, the syndrome is life threatening. Anti-α-Gal IgE antibodies induced by tick bites trigger the allergies. However, anti-α-Gal IgM antibodies induced by microbiota bacteria protect against infectious diseases. Professor José de la Fuente and Dr Alejandro […]

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