Mtb Archives

Pulmonary tuberculosis: Biomarker discovery in the quest for new therapies

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Dr Esmeralda Juárez and her team research tuberculosis disease mechanisms through biomarker discoveries.

Pulmonary tuberculosis (TB) presents a significant health burden worldwide with treatments remaining suboptimal. In the pursuit of new or adjunctive therapies, Esmeralda Juárez and researchers at the Department of Research in Microbiology at the National Institute of Respiratory Diseases in Mexico City investigate the lungs’ immune-response mechanisms to TB infection. By sampling the breath of TB patients using a non-invasive […]

Chemical synthesis to tackle tuberculosis

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Dr Jeffrey Buter has been researching the chemical biology of the parasite that causes TB to understand how the particular cell wall of Mtb enables it to avoid the immune response of the host

Tuberculosis (TB) – the world’s most deadly bacterial infectious disease – kills around 1.5 million people every year, and its treatment remains challenging. Dr Jeffrey Buter at the University of Groningen, the Netherlands, has been researching the chemical biology of Mycobacterium tuberculosis (Mtb), the parasite that causes TB. Buter believes that understanding the structure–activity relationship of the components, in particular […]