Health & Medicine

Exosome microRNAs as liquid biopsies for the monitoring of prostate cancer

Neuroendocrine prostate cancer (NEPC) is a highly aggressive variant of prostate cancer that emerges in response to hormone therapy. Dr Sharanjot Saini and her staff, from the Medical College of Georgia at Augusta University, USA, are studying exosomes – nano-sized vesicles that transfer lipids, proteins, or genetic information between cells. These could be used as a source of biomarkers to […]

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Health & Medicine

The silent pandemic: Addressing antimicrobial resistance

Antimicrobial resistance (AMR) is a silent pandemic that poses a huge threat to global health and development. The World Health Organization and its partner organisations are seeking to raise awareness of the issue. One approach is through annual monitoring of progress through the Tripartite AMR Country Self-Assessment Survey (TrACSS), for which the 2021 results are now available, www.amrcountryprogress.org. While significant […]

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Health & Medicine

AMP-activated kinase as a therapeutic target in prostate cancer

Pharmacological treatment of prostate cancer has advanced significantly in recent years. However, while the newest therapies are initially effective in reducing tumour size, most patients eventually develop drug resistance and the recurrence of malignant spread. Professor Inés Díaz-Laviada and her team at the Alcala University in Madrid, Spain, have demonstrated that long-term treatments may induce the transformation of cancer cells […]

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Health & Medicine

Using a computer to fight malaria: Finding new artemisinin-based combination therapies

Malaria still claims the lives of hundreds of thousands of people a year and the World Health Organisation identifies half the world’s population at risk from the disease. Even more worryingly, an increasing number of malaria strains are showing signs of drug resistance to existing treatments. One approach that still seems to be effective is the use of artemisinin-based combination […]

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