Tag: NaV1.4 voltage-gated sodium channel

Genetic evidence implicates respiratory muscle dysfunction in SIDS

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Mr Pontus Sirens highlights genetic evidence about the role that respiratory muscles play in the etiology of SIDS, and highlights the importance to investigate how the diaphragm may impact SIDS

The SIDS-Critical Diaphragm Failure (SIDS-CDF) hypothesis posits that all SIDS risk factors either increase the workload of the diaphragm or reduce its force-generating capacity, and that while SIDS has many contributing factors, it has one cause, namely the failure of the vital respiratory pump. Several SIDS risk factors can impair diaphragm function, but especially noteworthy are the prone sleeping position […]

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