Tag: next-generation sequencing
Understanding plant pathogens using optical mapping
Macrophomina phaseolina MS-6 is a fungal pathogen responsible for causing a plethora of despairing diseases in more than 500 host plants, such as jute. A detailed study of the organism is vital for understanding mechanisms of infection in these plants. Whole-genome sequencing can aid this process and provide a better understanding of MS-6. Previously used sequencing methods like next-generation sequencing […]
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High-throughput fluorescent sequencing of biomolecules within their cellular environment
Understanding the molecular diversity within healthy or diseased tissues is crucial for the diagnosis and treatment of diseases and for gaining a better understanding of fundamental biological processes. Biological tissues contain thousands of different molecules, yet conventional staining looks at only a few at a time because it relies on a limited number of dyes. Prof George Church and Dr […]