Why do women experience more chronic pain than men?

Dr Singh investigates chronic pain, emphasising the need to understand the sex differences in chronic pain better.

Chronic pain is poorly managed by current healthcare systems, with limited treatments. However, little is known about chronic pain, especially in autoimmune diseases. Dr Gurmit Singh and colleagues at McMaster University, Canada, have investigated whether chronic pain should be considered an autoimmune disease and why chronic pain is more common in women. They have identified various explanations as to why women […]

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Identification of a novel key player in lupus disease opens the door to treatment

Professor Shiozawa identified a key inducer of lupus disease.

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, the precise cause of which is still unclear. Through dedicated work, Professor Shunichi Shiozawa from Kobe University, Japan, uncovers the underlying cellular and molecular mechanisms of systemic autoimmunity and identifies a novel key player. Shiozawa demonstrates that overstimulation of the host’s immune system by an immunogenic pathogen kickstarts the generation of […]

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Epidemiological data on systemic lupus erythematosus in Native sub-Saharan Africans

Value of the data This article provides an in-depth analysis of the data on systemic lupus erythematosus in Native sub-Saharan Africans. These data are beneficial for health professionals and researchers involved in systemic lupus erythematosus management and research, as well as local health authorities. As these data inform on the burden and management of systemic lupus erythematosus in Native sub-Saharan […]

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Systemic lupus erythematosus in native sub-Saharan Africans: A systematic review and meta-analysis

SLE

Background: The prevalence and phenotype of systemic lupus erythematosus (SLE) have not been thoroughly investigated in Native sub-Saharan Africans despite knowledge that the highest burden of SLE occurs in people of African descent. Through this systematic review of literature and meta-analysis, we wished to fill this gap. Methods: PubMed, EMBASE, Web of Science, African Journals Online, and Global Index Medicus, […]

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