Quality of life for family caregivers is impacted by satisfaction with care

Cancer does not only affect the patient but their caregiver.

Cancer has an emotional and physical impact on caregivers as well as patients. If relatives are not happy with the care they are able to provide for the patient, this can impair their quality of life. Dr Miki Morishita-Kawahara at the Tokyo Women’s Medical University aims to understand better the factors that influence the quality of life of family caregivers […]

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How did the data propagate? Automated Optical Path Monitoring

Optical fibre cables facilitate high-speed data transfer.

With the development of 5G, our world might seem more wireless than ever. However, lurking behind this and facilitating all high-speed data transfer are kilometres and kilometres of optical fibres. The backbone network for all communication, wireless or otherwise, is this sprawling network of fibres. For reliable communications and internet access, the world’s expanse of fibre optic cables must work […]

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Soil and groundwater contamination: An old and new issue needs to be solved

Industrial and agricultural waste contaminate the soil and groundwater.

Dr Ming Zhang is an innovation coordinator at Geological Survey of Japan, AIST. Alongside his research group, he is advocating the importance of using interdisciplinary tools for sustainable remediation of contaminated soil and groundwater. Their research has shown that cost-effective and environment-friendly technologies such as the use of microorganisms to degrade organic contaminants and the use of minerals to immobilise […]

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A focus on beta cell mass could help prevent type 2 diabetes

A focus on beta cell mass could help prevent type 2 diabetes

Diabetes is a global health problem expected to affect nearly seven percent of the world’s population by 2035. Treatment broadly focuses on regulating glucose levels, and an increase in the range of pharmacological options means that it is usually possible to manage the condition. However, diabetes cannot be cured. Professor Yoshifumi Saisho from Keio University, Japan, advocates moving the focus […]

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Crystal engineering for solid-state molecular recognition

for solid-state molecular recognition

Host-guest interactions in crystalline frameworks can be exploited to selectively and reversibly adsorb molecular species within a crystalline lattice. This process is important in a variety of technological fields, including gas separation, catalysis, trapping of pollutants and carbon capture. Professor Akiko Hori (Shibaura Institute of Technology) is developing chemical approaches for optimising the building blocks of these solid-state systems. Perfluorination […]

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Lighting Up Iridium Complexes

Ir-containing molecules have proved very popular for OLED devices.

Iridium (Ir) is a fascinating element. A rare metal found in the Earth’s crust, Ir can bond with a variety of other elements to make different metal complexes. Such complexes have unusual and interesting interactions with light, with many complexes exhibiting strong luminescence on long timescales. This has made them widely used as molecules for bioimaging probes and organic light […]

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Predicting post-seismic liquefaction through geological response analysis

During liquefaction, solid sandy ground behaves like a liquid.

During liquefaction, solid sandy ground behaves like a liquid, posing a significant threat in earthquake-prone regions. Seismic waves cause water-saturated sandy sediments to flow, resulting in ground subsidence and flooding. To address gaps in our understanding, Prof Yukitake Shioi from the Hachinohe Institute of Technology in Japan applied a finite element method model to observations from the 1994 Far-Off Sanriku […]

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Fragment-based design of isoquinoline derivatives as anti-inflammatory drugs

Dr Masakazu Atobe and his colleagues have developed a methodology that can be applied to the discovery of effective drugs.

Fragment-based drug discovery (FBDD) is a well-established high-throughput screening method for drug generation. Fragment molecules used in FBDD tend to be structurally less complex than the compounds used in conventional high-throughput screening techniques. Dr Masakazu Atobe from Asahi Kasei Pharma Corporation in Japan and his colleagues have developed a methodology that can be applied to the discovery of effective drugs […]

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Cell culture protocols for growing human keratinocytes in the laboratory

Dr Hitomi Fujisaki studies human epidermal keratinocytes (skin cells).

Dr Hitomi Fujisaki, Senior Research Scientist at Nippi Research Institute of Biomatrix in Japan, studies human epidermal keratinocytes (skin cells) and cancer cells using two- and three-dimensional type I collagen substrates. Through her research, she aims to understand more about the ways in which these cells interact with the substrate that they are grown on, and how this relationship can […]

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The child deficit and the changing value of children in Asia

In most Asian countries, average family size has more than halved over the past six decades.

Since the 1960s, Asia has experienced a dramatic decline in fertility rates. Philip Morrison, Professor Emeritus at Victoria University of Wellington, New Zealand, asks whether this shift has been accompanied by a reduction in the value of children as inferred from the European experience. If so, one might expect a convergence of the ideal and actual family size and a […]

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