Leaving a legacy of ill health: The trans-generational effects of smoking

smoking causes trans-generational transmission of ill-health

The University of Bristol is a respected authority in research at the intersection of epigenetics and epidemiology. Founded by Jean Golding, Emeritus Professor of Paediatric and Perinatal Epidemiology, the Avon Longitudinal Study of Parents and Children (ALSPAC, also known as Children of the 90s) is one of the world’s most comprehensive ongoing data sets spanning generations. Findings from this multi-generational […]

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Carcinogenesis: When transmission of epigenetic information goes awry

Professor Patrick Riley Research Outreach

Genes are blueprints that code for proteins and in turn, proteins drive most activities within our cells. But between genes and their protein products is the layer of epigenetics – genes may be expressed differently depending on the heritable, epigenetic features that switch them on and off. Charting new territories in carcinogenesis, Professor Patrick Riley at University College London explores […]

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The epigenetic effects of adverse early-life experiences

Dr Roth’s work explores the impact our environment, specifically stress, on our genes and how these epigenetic changes affect early life experiences.

Environmental factors interact with genetics in driving living organisms’ development throughout life. Epigenetics is the field of study that explores this interaction, as well as its potential effects on individuals’ behaviour and health. Dr Tania Roth, working at the University of Delaware in Newark, USA, carried out extensive research exploring the impact of the environment, particularly stress factors, on individual […]

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