A new 3D hybrid model for epithelial morphogenesis

cells through a microscope

Wound healing is a biological mechanism that allows the integrity and functionality of tissues to be preserved. Dr Jose Muñoz, Associate Professor at the Laboratory of Numerical Analysis (LaCàN), Universitat Politècnica de Catalunya, Spain, models the three-dimensional mechanisms involved in wound healing. In this research, these three-dimensional mechanisms are simulated with a hybrid vertex model. Supported by experimental observation, the […]

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Inflammatory bowel disease and epithelial barrier function

Inflammatory bowel disease and epithelial barrier function

Inflammatory bowel disease (IBD) occurs when the epithelial cells lining the gut become weakened, allowing gut microbes to activate immune cells. Gut barrier weakening can be caused by a loss of function of the PTPN2 gene. Professor Declan McCole of the University of California, Riverside and various collaborators have extensively researched the role of the epithelial barrier in IBD, the […]

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