Identification of a novel key player in lupus disease opens the door to treatment

Professor Shiozawa identified a key inducer of lupus disease.

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, the precise cause of which is still unclear. Through dedicated work, Professor Shunichi Shiozawa from Kobe University, Japan, uncovers the underlying cellular and molecular mechanisms of systemic autoimmunity and identifies a novel key player. Shiozawa demonstrates that overstimulation of the host’s immune system by an immunogenic pathogen kickstarts the generation of […]

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Reactive oxygen species are at the heart of innate immunity

Reactive oxygen species are at the heart of innate immunity

Our innate immune system is our first line of defence against disease. At the heart of this response is an enzyme complex, called NADPH oxidase, which produces a form of reactive oxygen molecule to destroy invading pathogens. Professor Edgar Pick of Tel Aviv University, has made a huge contribution to this field of research, enhancing our understanding of the foundations […]

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