Raising antibodies against protein complexes

A health research article about Dr LaCava researches macromolecular interactions analyses, developing monoclonal antibodies capable of binding to protein complexes found in cancer cells.

Dr John LaCava of The Rockefeller University has identified a gap in the current availability of target-specific antibodies for the analysis of intracellular protein-protein interactions. Using the latest antibody production techniques, alongside immunoprecipitation and mass spectrometry, he aims to identify important interactions between transcription factors and other macromolecules which are implicated in disease. Proteins are vital for the inner workings […]

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