macrophages Archives

Nanoparticles as Trojan horses: A safe and effective way to deliver oncolytic viruses to treat all cancers

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Tumour microenvironment, including immune cells and fibroblasts.

Advanced cancer often comes with a lack of treatment options. Immunotherapies like cancer-killing viruses – oncolytic viruses (OVs) – are becoming increasingly popular but are currently limited by their inability to be administered into the blood. However, Dr Faith Howard and Dr Munitta Muthana, researchers at the University of Sheffield in the UK, demonstrate that OVs can be injected into […]

Pulmonary tuberculosis: Biomarker discovery in the quest for new therapies

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Dr Esmeralda Juárez and her team research tuberculosis disease mechanisms through biomarker discoveries.

Pulmonary tuberculosis (TB) presents a significant health burden worldwide with treatments remaining suboptimal. In the pursuit of new or adjunctive therapies, Esmeralda Juárez and researchers at the Department of Research in Microbiology at the National Institute of Respiratory Diseases in Mexico City investigate the lungs’ immune-response mechanisms to TB infection. By sampling the breath of TB patients using a non-invasive […]