The role of extra chromosomal circular DNA in rapid adaption to glyphosate resistance in pigweed

eccDNAs could constitute the targets of the next generation of herbicides and anti-cancer drugs.

Plants, like other living organisms, have genetic stress-avoidance mechanisms that allow them to become resistant to specific chemicals when continuously exposed to them. Dr Christopher Saski from Clemson University and Dr William Molin from the U.S. Department of Agriculture are researching the extrachromosomal circular DNA (eccDNA) structure known as the replicon of pigweed, which contains the EPSPS gene, the gene […]

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Targeting melanoma cells with a drug-infused graphene matrix

The researchers are developing testing platforms for novel therapeutic drug combinations for patients with metastatic melanoma.

Dr Livia Sima of the Institute of Biochemistry of the Romanian Academy and Dr Emanuel Axente of the National Institute for Laser, Plasma, and Radiation Physics in Romania are developing novel platforms for screening of therapeutic drug combinations for patients with metastatic melanoma. Their most recent work involves investigating a method which can be used to screen potential drug candidates. […]

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