Exploring a novel approach to lung cancer treatment

the BMA process

Lung cancer, just like other types of cancer, is mostly treatable when diagnosed in the earliest stages. Treatments mainly include chemotherapy and surgeries such as sublobar resection and lobectomy. The thoracic surgical team led by Dr Calvin Ng at Prince of Wales Hospital, The Chinese University of Hong Kong, have successfully applied a novel approach to lung cancer treatment. They […]

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AMP-activated kinase as a therapeutic target in prostate cancer

Prostate cancer is one of the leading causes of mortality among men worldwide.

Pharmacological treatment of prostate cancer has advanced significantly in recent years. However, while the newest therapies are initially effective in reducing tumour size, most patients eventually develop drug resistance and the recurrence of malignant spread. Professor Inés Díaz-Laviada and her team at the Alcala University in Madrid, Spain, have demonstrated that long-term treatments may induce the transformation of cancer cells […]

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The adaptive cancer cell: How metastases evolve to resist treatment

PACCs make up a rare but stable population in standard cell culture.

Species adapt to survive in a changing environment through the process of evolution. Evolutionary processes can also take place at the cellular level. Dr Sarah Amend of Johns Hopkins University, Baltimore, USA, is investigating poly-aneuploid cancer cells (PACCs). These large, DNA-laden cells, which are more common in metastatic cancer, develop evolvability: the capacity to evolve. Dr Amend believes that targeting […]

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Halalopathy: Integrating mind, behaviour and health

Dr Alzeer believes that the principles of halalopathy will allow the right treatment to be matched to the right patient, allowing for a more effective therapy.

With the current focus on personalised medicine, some physicians are searching for new ways to treat the patient as an individual. Dr Jawad Alzeer of the University of Zurich, Switzerland, proposes a novel approach to medicine: halalopathy. Under halalopathy, mind, behaviour and health are fundamentally connected. By prioritising the relationships between these three aspects of a person, Dr Alzeer believes […]

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Transtympanic injections to prevent hearing loss caused by cisplatin

Combination therapies with an otoprotectant may help to prevent hearing loss caused by chemotherapeutic agent cisplatin.

Dr Sofia Waissbluth from The Pontificia Universidad Católica de Chile is specialised in otolaryngology (conditions of the head and neck). She has reviewed clinical trials that use transtympanic injections to prevent hearing loss caused by the chemotherapeutic agent cisplatin. To date there is no ‘one-shot’ solution to protect or cure patients from hearing loss. However, combinational therapy using transtympanic injections […]

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Unravelling the secrets of the cell with suspended microchannel resonators

Unravelling the secrets of the cell with suspended microchannel resonators

Researchers can learn much about the properties of many materials simply by weighing them. In cell biology, repeatedly measuring the mass of a cell reveals how fast the cell grows. However, this is very challenging: the mass of a single-cell is extremely difficult to measure with enough accuracy and without perturbing the cell. The laboratory of Dr Scott Manalis at […]

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