mRNA Archives

Resilience, scepticism, and mRNA: The story of Katalin Karikó

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Katalin Karikó mRNA vaccines for COVID-19

The COVID-19 pandemic presented the world’s governments and health organisations with a vaccination challenge on a scale it had never experienced before. Messenger RNA (mRNA) vaccines were critical in the production and distribution of affordable vaccines across the globe. Katalin Karikó’s 40 years of research into mRNA was the cornerstone of what made this possible. In this interview, we find […]

Pathbreaking method leads to optimised mRNA production

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Dr Sekirnik and his team at Sartorius BIA Separations optimised a crucial step in the mRNA production process, resulting in higher yield at lower cost.

The COVID-19 pandemic placed mRNA at the centre of biopharmaceutical research, as mRNA is now being developed for cancer therapy, protein replacement therapy, and infectious diseases. That is why, worldwide, the need to produce mRNA on a large scale has increased dramatically. The currently used method is quite costly, limiting the scale-up of mRNA production. Dr Rok Sekirnik and colleagues […]

Housekeeping rules: Why reference genes matter in jute plants

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Jute is a commercially grown fibre plant that provides a natural resource for modern day fibre usage. With the lack of diversity in jute plants, the recent sequencing of the jute genome offers a wide range of gene targets for crop breeding. In parallel, the use of quantitative approaches to study the expression pattern of jute genes has taken precedent. […]