A mathematical model to predict cancer nanomedicine delivery

graphic of nanoparticles

Dr Zhihui Wang is a researcher at the Houston Methodist Research Institute. He is a leading expert in the fields of computational biology, modelling-aided drug target discovery, biophysical modelling of drug transport, and multiscale cancer modelling. Together with Dr Prashant Dogra, the team have developed a computational model that improves our understanding of the relationship between key nanoparticle properties, the […]

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Can cognitive impairments caused by methamphetamine use perpetuate the addiction cycle?

Dr Reichel is investigating the cognitive and neural underpinnings of substance use disorders.

The repeated use of methamphetamine, or meth, is known to cause significant changes in the brain and cognitive impairments, which might strengthen or perpetuate a user’s addiction. Dr Carmela Reichel at the Medical University of South Carolina has conducted extensive research investigating the relationship between motivated meth use, meth-induced cognitive dysfunctions, and relapse. Her work has highlighted a number of […]

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When control is lost: Studying the interactions of ATP and acetylcholine in the urinary bladder

The inner lining of the bladder, known as the urothelium, triggers the reflex controlling urination.

The inner lining of the bladder, known as the urothelium, not only serves as a passive barrier but also triggers the reflex controlling urination (the micturition reflex). The neurotransmitter ATP released from the stretched urothelium activates the bladder afferent nerves and evokes the release of acetylcholine that substantially contributes to the contractile response. Prof Gunnar Tobin from the University of […]

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Careers in Science: Summer Training in Environmental and Pharmacological Sciences (STEPS)

STEPS research outreach

The future of scientific research depends on a talented, diverse and inclusive workforce with high scientific proficiency. Undergraduate research experiences have been shown to play a key role in encouraging students, especially those from historically underrepresented groups, to pursue careers in science and healthcare professions. In response to these needs, Professor Hollie Swanson, from the University of Kentucky has developed […]

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