Rethinking the Tree of Life with new tools

Dr Sung-Hou Kim has applied a new way of thinking to an old model, the Tree of Life, which dates back to Darwin.

Professor Sung-Hou Kim and his colleagues from the University of California, Berkeley, have applied a new way of thinking to the Tree of Life, a concept that has been around since Darwin’s time. Drawing from their collective expertise, they applied an Information Theory-based non-alignment method to compare whole-proteome sequences, the protein sequences coded by all genes of each organism. Their […]

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High-throughput fluorescent sequencing of biomolecules within their cellular environment

The researchers have developed FISSEQ to sequence barcodes which can be placed in the mouse brain.

Understanding the molecular diversity within healthy or diseased tissues is crucial for the diagnosis and treatment of diseases and for gaining a better understanding of fundamental biological processes. Biological tissues contain thousands of different molecules, yet conventional staining looks at only a few at a time because it relies on a limited number of dyes. Prof George Church and Dr […]

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