Tag: SIDS-CDF
Genetic evidence implicates respiratory muscle dysfunction in SIDS

The SIDS-Critical Diaphragm Failure (SIDS-CDF) hypothesis posits that all SIDS risk factors either increase the workload of the diaphragm or reduce its force-generating capacity, and that while SIDS has many contributing factors, it has one cause, namely the failure of the vital respiratory pump. Several SIDS risk factors can impair diaphragm function, but especially noteworthy are the prone sleeping position […]
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The missing link? Sudden infant death syndrome and the diaphragm

The cause of death in sudden infant death syndrome (SIDS) is unknown. Scientists know that risk factors include the prone sleeping position, prematurity, low birth weight, and non-lethal infections. SIDS likely has a respiratory origin, but the diaphragm that powers the vital respiratory pump has not been adequately investigated in the context of SIDS. Diaphragm failure is a well-known cause […]
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