Cryo-electron tomography and synaptic transmission in the brain

The transfer of information between neurons in the brain occurs via a carefully regulated release of chemical neurotransmitters.

The transmission of information between brain cells is regulated by complex loops of biochemical processes. Neurotransmitter molecules are released in the intercellular space by an electrically stimulated neuron and bind to receptors in a different neuron, thus establishing a connection between these cells. By combining cryo-electron microscopy and tomography of vitrified brain samples, Dr Vladan Lučić at Max Planck Institute […]

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