tumour microenvironment Archives

Placental immune editing switches (PIES) and cancer progression

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Exceptional mechanisms have evolved over millions of years to allow the foetus to grow directly inside the mother’s womb. These mechanisms, named placental immune editing switches, are orchestrated by the placenta and are responsible for locally switching off the mother’s immune system to protect the foetus. However, Dr Miguel Hernández-Bronchud from Clínica Corachan in Barcelona, suggests that the existence of […]

A shining light in the fight against childhood leukaemia?

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Dr C. James Lim, PhD, is an Associate Professor at the Department of Pediatrics, University of British Columbia, as well as Investigator at the Michael Cuccione Childhood Cancer Research Program at British Columbia Children’s Hospital, Vancouver, Canada. His research group aims to unravel the mechanisms underlying acquired resistance to chemotherapy in childhood malignancies, with the goal of identifying new treatment […]