X-ray ptychography: Seeing chromosome abnormalities in a new light

Ian Robinson has investigated the masses of irradiated metaphase chromosomes using a novel method called X-ray ptychography

Chromosome abnormalities have profound health consequences including trisomy and cancer. Karyotyping (the visualisation of the complete set of chromosomes by shape and size) is an initial step towards identification of chromosome aberrations and disease. Other chromosome imaging methods such as fluorescent in situ hybridisation (FISH) rely on sample preparation or fluorescent markers, which may or may not alter the sample. […]

Read More… from X-ray ptychography: Seeing chromosome abnormalities in a new light

The intricate world of the centrosome

microtubules inside cells

Dr Ryoko Kuriyama is a Professor at the University of Minnesota, Twin Cities. Alongside Dr Cody Fisher, she studies mammalian centrosomes, composite organelles responsible for the segregation of chromosomes during mammalian somatic cell division. Together, Kuriyama and Fisher, with the help of the United States National Science Foundation, investigate the detailed complexity of centrosome maturation, identifying the pericentriolar material protein […]

Read More… from The intricate world of the centrosome

A hitherto unseen matrix involved in cell division is revealed

A hitherto unseen matrix involved in cell division is revealed

Cell division has been fascinating researchers for decades. This process could not occur without the spindle to organise the chromosomes neatly in two sets, one for each daughter cell. It’s commonly accepted that the spindle is formed by a series of filaments that puts chromosomes into place, but there may be more to it than that. This is certainly the […]

Read More… from A hitherto unseen matrix involved in cell division is revealed