X-ray ptychography: Seeing chromosome abnormalities in a new light

Ian Robinson has investigated the masses of irradiated metaphase chromosomes using a novel method called X-ray ptychography

Chromosome abnormalities have profound health consequences including trisomy and cancer. Karyotyping (the visualisation of the complete set of chromosomes by shape and size) is an initial step towards identification of chromosome aberrations and disease. Other chromosome imaging methods such as fluorescent in situ hybridisation (FISH) rely on sample preparation or fluorescent markers, which may or may not alter the sample. […]

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Energy transformation in living cells: The role of vitamin C

Professor János Hunyady has formulated how ATP is synthesised in cells, the energy present in cells, and how the structures for energy transformation regulate ATP production in aerobic and anaerobic conditions

The biochemical processes responsible for energy production in cells and for its utilisation in cellular metabolism have been studied extensively. Although several details of how these complex chemical reactions take place have progressively been clarified, far less is known about the structure of the biomolecules involved and their interactions. Professor emeritus János Hunyady, from the University of Debrecen, Hungary, is […]

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