metabolic diseases Archives

Metabolic dysfunction: The liver and beyond

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Philipp Kaldis and colleagues have conducted extensive research to elucidate the mechanisms of liver diseases, focusing on metabolism and interorgan crosstalk.

The liver is the centre of our metabolism, with metabolic dysfunction playing a pivotal role in liver diseases and type 2 diabetes. Despite extensive study, the mechanisms underlying these pathologies remain largely unexplained. Professor Philipp Kaldis of Lund University, Sweden, has collaborated with fellow researchers to investigate the role of metabolites during metabolic dysfunction in these diseases. Motivated by the goal […]

Optimal lipid metabolism with disease-preventing functional foods

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Professor Harjinder Singh and Dr Alexander Acevedo-Fani research lipid digestion and the possibility of altering emulsion interactions

Dietary lipids (fats) from plant and animal sources are important components of the human diet as they provide essential nutrients for growth and development. However, overconsumption of lipid-rich foods can lead to hyperlipidaemia – a key risk factor for metabolic diseases, such as cardiovascular diseases and diabetes. Modulating lipid digestion and absorption through the design of food structures, matrices and […]

The carotid body: A candidate for regaining glucose tolerance in Type 2 diabetes

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Professor Silvia Conde and her team from the NOVA Medical School, NOVA University of Lisbon, have proposed a new strategy for treating metabolic diseases. Previously, they showed that an over-active homeostasis sensor called the carotid body could cause insulin resistance and disrupt glucose tolerance, common in Type 2 diabetes. In their new study, Prof Conde’s team applied a kilohertz frequency […]