non-alcoholic fatty liver disease Archives

Metabolic dysfunction: The liver and beyond

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Philipp Kaldis and colleagues have conducted extensive research to elucidate the mechanisms of liver diseases, focusing on metabolism and interorgan crosstalk.

The liver is the centre of our metabolism, with metabolic dysfunction playing a pivotal role in liver diseases and type 2 diabetes. Despite extensive study, the mechanisms underlying these pathologies remain largely unexplained. Professor Philipp Kaldis of Lund University, Sweden, has collaborated with fellow researchers to investigate the role of metabolites during metabolic dysfunction in these diseases. Motivated by the goal […]

Is the magic in the muscle? Targeting skeletal muscle to improve cardiometabolic function in ageing

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The Butcher Lab investigates the interplay of muscle mass and skeletal muscle on cardiovascular disease, obesity and ageing.

Dr Joshua T Butcher and his team from the Oklahoma State University College of Veterinary Medicine, USA, investigate the similarities between the co-morbidities associated with obesity and ageing, and specifically how skeletal muscle mass and function can be used to uncouple diseases from accompanying pathology. While we all know that exercise is beneficial for weight loss, an important underlying benefit […]