Using genetics to guide treatment of arterial hypertension with Rostafuroxin

Many genetic variants have been found to be associated with blood pressure level.

Primary hypertension is a major health concern and can cause serious cardiac, renal and brain complications responsible for about 10% of worldwide health burden and costs. The development of hypertension is triggered by genetic factors that, in turn, are modulated by biological and environmental factors. Many drugs are available for the treatment of hypertension, but none target the underlying genetic […]

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Blood, skin and bone: the complex control of blood pressure

It is well-known that excessive salt intake can be a risk factor for high blood pressure. But how this effect is mediated – and why some people are more susceptible than others – remains up for debate. Collaborators Professor Raymond Harris and Professor Ming-Zhi Zhang, at Vanderbilt University School of Medicine, have uncovered a novel role for immune cells derived […]

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