A new method to predict adult-onset type 1 diabetes

Dr Liping Yu identifies a new method for identifying adult-onset type 1 diabetes using a more efficient method of detecting GADA autoantibodies

Adult-onset type 1 diabetes is an autoimmune disease often mistaken for type 2 diabetes. Distinguishing adult-onset type 1 diabetes from type 2 diabetes is vital so that appropriate treatment can begin immediately. This is mainly achieved by identification of GADA, an islet autoantibody found in patients with adult-onset type 1 diabetes. A radio-binding assay is currently used for GADA detection, […]

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Could a serpin antibody help to treat type 1 diabetes?

Could a serpin antibody help to treat type 1 diabetes? Investigating the connection between inflammation and tissue regeneration.

Research from Dr Jan Czyzyk and his team at the University of Minnesota, USA, explores the balance between proteases and serpins, and how their activity can in turn affect the inflammation and tissue regeneration of pancreatic islet cells. Their findings show that antibodies can be used to change this serpin–protease balance, with interesting impacts. Excitingly, their research opens the possibility […]

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How parent relationships could hold the key to managing type 1 diabetes

Type 1 diabetes is a lifelong condition that can have profound effects on quality of life. Managing it effectively with insulin is key to keeping healthy; however, adherence is often easier said than done, especially with young adults. Prof Cynthia Berg and clinical psychology doctoral student MaryJane Simms Campbell at the University of Utah are leading pioneering research revealing how […]

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Flexibility is key in treating children with type 1 diabetes

Blood vessels

People with type 1 diabetes cannot produce their own insulin, leading to uncontrolled blood sugar levels. To survive, they must receive insulin treatment. A recently developed, long-lasting insulin called degludec offers a unique level of flexibility. This means that it is particularly suitable for treating children and young people with type 1 diabetes. Dr Nandu Thalange, an expert in childhood diabetes […]

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