Tag: Amyotrophic lateral sclerosis
Using β3 integrin to control reactive astrocytes, and help neurons survive
The long-ignored astrocyte is of more interest than ever in neuroscience. When the central nervous system is damaged, astrocytes undergo astrogliosis, morphing into reactive astrocytes to protect neurons from further damage. But, as it turns out, this process could be doing more harm than good by not allowing damaged neurons to mend themselves. Professor Lisette Leyton of the University of […]
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Fruit flies help shed light on drug discovery for ALS
Amyotrophic lateral sclerosis (ALS) is a devastating and incurable neurodegenerative disease that affects people in adulthood. It leads to the death of neurons involved in muscle control, eventually affecting almost all facets of the body, including walking, swallowing and breathing. Drs Nancy Bonini and Leeanne McGurk at the University of Pennsylvania are using fruit flies, mammalian cellular systems like neurons, […]
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