chemoresistance Archives

CRISPR gene editing: Can we make cancer cells easier to kill?

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Researchers at the Gene Editing Institute have developed a CRISPR gene editing tool to disable genes causing resistance to standard care in cancer patients.

Lung cancer accounts for approximately one in five cancer deaths globally. The high death toll makes the development of new treatments and improvement of old ones a top priority. One of the challenges with traditional chemotherapy is that tumours can develop resistance to treatment. For several years, Eric B Kmiec, PhD, at the Gene Editing Institute of ChristianaCare, USA and […]

A shining light in the fight against childhood leukaemia?

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Dr C. James Lim, PhD, is an Associate Professor at the Department of Pediatrics, University of British Columbia, as well as Investigator at the Michael Cuccione Childhood Cancer Research Program at British Columbia Children’s Hospital, Vancouver, Canada. His research group aims to unravel the mechanisms underlying acquired resistance to chemotherapy in childhood malignancies, with the goal of identifying new treatment […]