Is the magic in the muscle? Targeting skeletal muscle to improve cardiometabolic function in ageing

The Butcher Lab investigates the interplay of muscle mass and skeletal muscle on cardiovascular disease, obesity and ageing.

Dr Joshua T Butcher and his team from the Oklahoma State University College of Veterinary Medicine, USA, investigate the similarities between the co-morbidities associated with obesity and ageing, and specifically how skeletal muscle mass and function can be used to uncouple diseases from accompanying pathology. While we all know that exercise is beneficial for weight loss, an important underlying benefit […]

Read More… from Is the magic in the muscle? Targeting skeletal muscle to improve cardiometabolic function in ageing

The Thought Leader series: Interviewing esteemed global thinkers

A focus on the Thought Leaders that have been featured in Research Outreach publications

At Research Outreach, we strive to showcase a wealth of cutting-edge research from across the sciences and beyond. As part of this uniquely exciting remit, we run the ‘Thought Leader’ series, interviewing esteemed thinkers, researchers, and communicators from world-leading organisations and a diverse array of disciplines. These interviews afford our readers the rare opportunity to hear about the latest research […]

Read More… from The Thought Leader series: Interviewing esteemed global thinkers

Blood–brain communication: Essential for regulation of autonomic nervous system and optimal health?

Professor Alastair V Ferguson researches blood–brain communication and s has focused on understanding how our brain controls many critical variables – including glucose, oxygen, blood pressure and electrolytes to maintain optimal body function and avoid issues with hypertension or obesity.

Professor Alastair V Ferguson leads an interdisciplinary neuroscience research group at Queens University in Canada, studying the central nervous system with a specific focus on understanding changes in brain function associated with hypertension and obesity. More specifically, the group’s recent studies have focused on understanding how our brain controls many critical variables – including glucose, oxygen, blood pressure and electrolytes […]

Read More… from Blood–brain communication: Essential for regulation of autonomic nervous system and optimal health?

Using genetics to guide treatment of arterial hypertension with Rostafuroxin

Many genetic variants have been found to be associated with blood pressure level.

Primary hypertension is a major health concern and can cause serious cardiac, renal and brain complications responsible for about 10% of worldwide health burden and costs. The development of hypertension is triggered by genetic factors that, in turn, are modulated by biological and environmental factors. Many drugs are available for the treatment of hypertension, but none target the underlying genetic […]

Read More… from Using genetics to guide treatment of arterial hypertension with Rostafuroxin

Blood, skin and bone: the complex control of blood pressure

It is well-known that excessive salt intake can be a risk factor for high blood pressure. But how this effect is mediated – and why some people are more susceptible than others – remains up for debate. Collaborators Professor Raymond Harris and Professor Ming-Zhi Zhang, at Vanderbilt University School of Medicine, have uncovered a novel role for immune cells derived […]

Read More… from Blood, skin and bone: the complex control of blood pressure