kidney disease Archives

Using genetics to guide treatment of arterial hypertension with Rostafuroxin

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Many genetic variants have been found to be associated with blood pressure level.

Primary hypertension is a major health concern and can cause serious cardiac, renal and brain complications responsible for about 10% of worldwide health burden and costs. The development of hypertension is triggered by genetic factors that, in turn, are modulated by biological and environmental factors. Many drugs are available for the treatment of hypertension, but none target the underlying genetic […]

Magnitude of uncontrolled hypertension, and associated factors, amongst adult hypertensive patients in public hospitals of Central Zone, Tigray, Ethiopia, 2018

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Uncontrolled hypertension For the general hypertensive population, uncontrolled hypertension (high blood pressure) is if the systolic blood pressure (SBP) is ≥140 mm Hg and/or diastolic blood pressure (DBP) is ≥90mm Hg. For inpatients with established diabetes mellitus or chronic kidney disease – it’s when SBP is ≥130 mm Hg and/or DBP is ≥80mm Hg. Blood pressure results are based on […]

A safer, effective treatment for autoimmune glomerulonephritis

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In the disease autoimmune glomerulonephritis, the body’s own immune system attacks the blood vessels of the glomeruli, the part of the kidney that filters the blood. This condition is life-threatening, but current treatments are limited and carry a high risk of serious side-effects. Recently, Dr Dragana Odobasic of Monash University, Melbourne, Australia, and her colleagues investigated the potential of tolerogenic […]