university of texas Archives

Drug-adapted RET mutations

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The active RET protein has been seen in many types of thyroid cancers.

RET is a protein tyrosine kinase that is upregulated and activated in many diverse forms of cancer. Treatments using RET-specific inhibitors have been highly effective, but the threat of resistance to these drugs looms. For this reason, Dr Jie Wu and Dr Blaine Mooers from the University of Oklahoma, together with Dr Vivek Subbiah from the University of Texas, decided […]

Smooth sailing: Wind, water, and Viking voyages

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Misconceptions about the Vikings are more numerous than facts, one being their portrayal as sailors blindly battling through cold, fog, wind, and turbulence. Through scientific research and their own voyage on the (not so) high seas, Professor William Doolittle (University of Texas) and Professor Stephen Stadler (Oklahoma State University) have dispelled this myth. Summertime winds and currents would not have […]

The importance of the autopsy in medicine

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Clinical autopsy is integral to public health, it has brought critical advances in the understanding of disease and its treatment, leading to improvements in many people’s lives and to many lives being saved. Despite this, there has been a gradual demise in the use of clinical autopsy in medical practice. Professor L. Maximilian Buja of the McGovern Medical School, University […]

New 3D technology to help in the battle against brain tumours

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Dr. Darin T. Okuda is a clinician-scientist and professor of Neurology and Neurotherapeutics at the University of Texas Southwestern Medical Center in Dallas. Dr. Okuda strives to transform healthcare by developing new diagnostic tools that challenge current clinical practices. His research group recently designed a novel method to visualise brain tumours in three-dimension (3D). This latest research aims to revolutionise […]

Novel 3D microscope provides unprecedented moving images of biological processes

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This article explores the work of Dr Chunqiang Li from the University of Texas at El Paso has developed a novel 3D optical microscope that uses a spectrally shaped pulse laser.

Dr Chunqiang Li and his team of the University of Texas at El Paso have developed a novel three-dimensional (3D) optical microscope that uses a spectrally shaped pulse laser. Whilst most prior microscopes used scanning to achieve high speed 2D imaging, Dr Li’s approach obtains the z-position from a technique called ‘temporal focusing’ that use ‘diffraction’ rings and clever mathematics […]